바이오상용기술고도화플랫폼 실증시험지원사업단

(1) High Resolution MS/MS system
1) The mass spectrometer is of a quadrupole - Quadrupole - TOF
configuration delivering high resolution and accurate masses at all modes of operation.
2) The mass spectrometer must be capable of real-time data acquisition and data processing, enabling a high spectrum repetition rate.
3) Performance specification must be provided as follows ;
- Resolution : maximum resolution of ≥50,000 (FWHM) using Q-TOF.
- Mass accuracy : ≤1 ppm RMS with external calibration over 24h and without any kind of mass recalibration ≤1 ppm RMS with internal calibration
- Sensitivity : 50 pg/μL Leucine enkephalin, Intensity >31,200 ion/sec Resolution 10,000 using SIM mode
4) Linear Dynamic Range : ≥10,000
5) Mass Range : 20 ~ 100,000 m/z for MS scan Resolution mode
(2) UPLC(Ultra performance liquid chromatography) system
1) Design : Independent dual Piston
2) Flow rate range : 0.01 to 2,000㎕/min(1 to 2,000㎕/min).
3) Flow rate accuracy : ≤±1.0%.
4) Flow rate precision : ≤0.075% RSD.
5) Pressure range : 18,000 psi.
6) Proportioning precision : ≤0.15% SD at 2mL/min.
7) Gradient delay volume : ≤ 100 ㎕.
8) Solvent degassing : ≥6-channels.
(3) Nano Flow LC System
1) Type : Independent dual Piston.
2) Flow range : 200nL to 100 uL/min without flow splitting
3) Pressure range : 15,000 psi.
4) Flow rate precision :<0.075%.
5) Dual-Gradient formation : Binary, reliable gradient performance, high pressure blending
6) Delay volume : <1ul(1,000nl).