1. Mass Spectrometer
(1) Mass Performance
1) Mass range : m/z 5 to 2,000 or better
2) Resolution : R < 0.7 u FWHM or less
3) Sensitivity
: ESI positive, 1pg reserpine, S/N > 1,000,000 : 1 or better
: ESI negative 1pg chloramphenicol, S/N > 1,000,000 : 1 or better
4) Measurement mode : Q1 Scan/SIM, Q3 Scan/SIM, MRM Precursor ion scan, Product ion scan
5) Mass stability : 0.05u/24hr or better
6) Minimum pause time : 1 msec or less
7) Minimum dwell time : 0.8 msec or less
8) Polarity switching time : 5 msec or less
9) Scan speed : 30,000 u/sec or better
10) MRM transition speed : Max. 555ch/sec or better
2. UHPLC System
(1) Solvent delivery unit
1) Pump : Micro-volume double plunger pump
2) Solvent delivery modes : Constant flow rate and constant pressure delivery
3) Max. Flow rate range : 0.0001 to 3.0000 mL/min (to 105MPa) or better
4) Flow rate accuracy : ± 1% or better
5) Flow rate precision : 0.06% RSD or less