Optix MX3은 Time Domain technology를 이용하여 Fluorescence의 picoseconds 단위의 시간차 반응을 구분하여 측정함으로써 실험동물 장기 내부의 target signal의 깊이와 농도를 구분하여 3D상에서 signal 분포에 대한 정보를 제공하는 in vivo imaging system입니다.

특장점
Fluorescence의 intensity, depth, concentration, lifetime 등의 다각도 분석 데이터 제공
3D 재조합 이미지를 제공하여 시료의 깊이별 분포 관찰
Target fluorescence의 lifetime을 기준으로 signal을 gating하여 autofluorescence를 완벽히 제거
Micro CT 데이터와 통합 가능하여 physiological reference 제공


적용분야
Oncology
Cardiovascular Disease
Neuroscience
ADMETox

Technical Specifications
Illumination source
Internal: one to four lasers, External: user-defined

Available laser wavelengths
Laser diode: 470 nm, 635 nm, 670 nm, 735 nm, 785 nm
CW laser: 532nm

Laser pulse rates
2.5; 5; 10; 20; 40 and 80 MHz ± 1%

Light pulse duration
≤ 150 ps

Maximum optical power
Pulsed laser: ≥ 1 mW in the range of 470 to 785 nm at 80 MHz
CW laser: ≥ 1 mW at 532nm

Detection system
Photomultiplier tube(PMT)
With Time-corelated single photon counting system(TCSPC)

Detection filters
Eight-position fluorescence filter wheels

Wavelength detection range
450 to 900 nm

Detection spot
1 mm diameter

Camera for the profile and visible image
CCD, monochrome XVGA

Number of pixels
1032 x 776

Scan step
0.5 to 3 mm

Scan area (W × L × H)
8 × 20 × 5 cm

Heated plate
Selectable and adjustable from 28 to 42 °C

Animal handling
Specimen presence monitoring
Specimen bed temperature monitoring control rate > 1 °C / minute
Integrated inlet and outlet ports for gas anesthesia

Accessories
Five-mouse scanning bed
Optical/CT common scan bed for Optical/CT fusion
Isolation box
Anesthesia system

System size (W × D × H)
70 × 76 × 75 cm